X-ray Crystal Structure Analyses of Biological Macromolecules. Recent Advances.

X-ray Analysis of Biological Macromolecules

Advances in Crystal Growth Techniques of Biological Macromolecules

The structural knowledge of some biological macromolecules helps to understand their mechanisms of working and their role on health sciences, food science and even their effect on the economy. In this work, some recent solutions to crystallogenesis for structural analysis (convective transport, counter-diffusion, the challenge of membrane protein crystallization, and high throughput techniques)...

X-Ray, Crystal Structure and Solution Phase Studies of a Polymeric SrII Compound

In the crystal structure of the title polymeric compound, [C42H38N6O33Sr5.2(H2O)]n, five independent metal atoms (Sr1-Sr5) have different coordination environments. The Sr1 and Sr5 atoms are nine coordinated and feature distorted tricapped trigonal-prismatic and capped square-antiprismatic geometries, respectively....

X-ray radiation damage to biological macromolecules: further insights.

Despite significant progress made over more than 15 years of research, structural biologists are still grappling with the issue of radiation damage suffered by macromolecular crystals which is induced by the resultant radiation chemistry occurring during X-ray diffraction experiments. Further insights into these effects and the possible mitigation strategies for use in both diffraction and SAXS...

Small-angle X-ray and neutron scattering by biological macromolecules.

be 35.1 kJ/mol (8.4 kcal/mol) for formation of the complex and 115.9 kJ/mol(27.7 kcal/mol) for dissociation of the complex. The kinetic results, as well as helping to describe and validate the model of hyaluronate-proteoglycan interaction, are also of value in the design of experiments. In the experiment shown in Fig. 1 equilibrium is only attained after approx. 1-lfh, as monitored by light-sca...